Learn R Programming

⚠️There's a newer version (3.1-168) of this package.Take me there.

nlme (version 3.1-78)

Linear and nonlinear mixed effects models

Description

Fit and compare Gaussian linear and nonlinear mixed-effects models.

Copy Link

Version

Install

install.packages('nlme')

Monthly Downloads

122,138

Version

3.1-78

License

GPL version 2 or later

Maintainer

R-core R-core@R-project.org

Last Published

March 31st, 2025

Functions in nlme (3.1-78)

Covariate

Assign Covariate Values
Covariate.varFunc

Assign varFunc Covariate
Matrix.pdMat

Assign Matrix to a pdMat Object
Dim.corStruct

Dimensions of a corStruct Object
Initialize

Initialize Object
Initialize.reStruct

Initialize reStruct Object
ACF

Autocorrelation Function
BIC.logLik

BIC of a logLik Object
Initialize.glsStruct

Initialize a glsStruct Object
Dim.pdMat

Dimensions of a pdMat Object
Coef

Assign Values to Coefficients
compareFits

Compare Fitted Objects
Variogram.corLin

Calculate Semi-variogram for a corLin Object
formula.reStruct

Extract reStruct Object Formula
augPred

Augmented Predictions
getCovariateFormula

Extract Covariates Formula
corFactor

Factor of a Correlation Matrix
formula.pdMat

Extract pdMat Formula
corMatrix.reStruct

Extract Correlation Matrix from Components of an reStruct Object
getData.gls

Extract gls Object Data
fitted.glsStruct

Calculate glsStruct Fitted Values
getGroups.corStruct

Extract corStruct Groups
fitted.lmeStruct

Calculate lmeStruct Fitted Values
comparePred

Compare Predictions
fitted.lmList

Extract lmList Fitted Values
fixed.effects

Extract Fixed Effects
getData

Extract Data from an Object
getGroups.gls

Extract gls Object Groups
getGroupsFormula

Extract Grouping Formula
intervals.lme

Confidence Intervals on lme Parameters
logDet

Extract the Logarithm of the Determinant
Names.reStruct

Names of an reStruct Object
logLik.gnlsStruct

Log-Likelihood of a gnlsStruct Object
pdFactor.reStruct

Extract Square-Root Factor from Components of an reStruct Object
plot.augPred

Plot an augPred Object
print.varFunc

Print a varFunc Object
predict.nlme

Predictions from an nlme Object
recalc

Recalculate Condensed Linear Model Object
recalc.varFunc

Recalculate for varFunc Object
Variogram.corSpher

Calculate Semi-variogram for a corSpher Object
recalc.corStruct

Recalculate for corStruct Object
Initialize.lmeStruct

Initialize an lmeStruct Object
lmeObject

Fitted lme Object
ACF.lme

Autocorrelation Function for lme Residuals
Names.formula

Extract Names from a formula
collapse

Collapse According to Groups
VarCorr

Extract variance and correlation components
as.matrix.corStruct

Matrix of a corStruct Object
varIdent

Constant Variance Function
allCoef

Extract Coefficients from a Set of Objects
getGroups.data.frame

Extract Groups from a Data Frame
getData.lmList

Extract lmList Object Data
pairs.lme

Pairs Plot of an lme Object
fitted.gnlsStruct

Calculate gnlsStruct Fitted Values
fitted.nlmeStruct

Calculate nlmeStruct Fitted Values
coef.pdMat

pdMat Object Coefficients
[.pdMat

Subscript a pdMat Object
logDet.reStruct

Extract reStruct Log-Determinants
corClasses

Correlation Structure Classes
getGroups

Extract Grouping Factors from an Object
nlmeStruct

Nonlinear Mixed-Effects Structure
residuals.gls

Extract gls Residuals
corRatio

Rational Quadratic Correlation Structure
gnlsStruct

Generalized Nonlinear Least Squares Structure
pdMatrix.reStruct

Extract Matrix or Square-Root Factor from Components of an reStruct Object
summary.gls

Summarize a gls Object
pairs.compareFits

Pairs Plot of compareFits Object
solve.reStruct

Apply Solve to an reStruct Object
intervals.lmList

Confidence Intervals on lmList Coefficients
corSymm

General Correlation Structure
Names.pdBlocked

Names of a pdBlocked Object
residuals.lme

Extract lme Residuals
Names

Names Associated with an Object
Variogram.corExp

Calculate Semi-variogram for a corExp Object
asTable

Convert groupedData to a matrix
getCovariate.data.frame

Extract Data Frame Covariate
corMatrix.pdMat

Extract Correlation Matrix from a pdMat Object
BIC

Bayesian Information Criterion
pdMatrix

Extract Matrix or Square-Root Factor from a pdMat Object
balancedGrouped

Create a groupedData object from a matrix
quinModel

Model function for the Quinidine data
as.matrix.pdMat

Matrix of a pdMat Object
phenoModel

Model function for the Phenobarb data
logLik.reStruct

Calculate reStruct Log-Likelihood
Variogram.corRatio

Calculate Semi-variogram for a corRatio Object
corNatural

General correlation in natural parameterization
varWeights.lmeStruct

Variance Weights for lmeStruct Object
logLik.lmList

Log-Likelihood of an lmList Object
getCovariate.varFunc

Extract varFunc Covariate
pdCompSymm

Positive-Definite Matrix with Compound Symmetry Structure
plot.ACF

Plot an ACF Object
coef.gnls

Extract gnls Coefficients
pairs.lmList

Pairs Plot of an lmList Object
as.matrix.reStruct

Matrices of an reStruct Object
fitted.lme

Extract lme Fitted Values
solve.pdMat

Calculate Inverse of a Positive-Definite Matrix
residuals.lmList

Extract lmList Residuals
logLik.glsStruct

Log-Likelihood of a glsStruct Object
pdConstruct.pdBlocked

Construct pdBlocked Objects
varWeights

Extract Variance Function Weights
varFixed

Fixed Variance Function
nlsList.selfStart

nlsList Fit from a selfStart Function
recalc.reStruct

Recalculate for an reStruct Object
Variogram

Calculate Semi-variogram
update.modelStruct

Update a modelStruct Object
getResponse

Extract Response Variable from an Object
Variogram.gls

Calculate Semi-variogram for Residuals from a gls Object
coef.modelStruct

Extract modelStruct Object Coefficients
logLik.lmeStruct

Log-Likelihood of an lmeStruct Object
corFactor.corStruct

Factor of a corStruct Object Matrix
getCovariate

Extract Covariate from an Object
predict.gnls

Predictions from a gnls Object
random.effects

Extract Random Effects
coef.varFunc

varFunc Object Coefficients
predict.gls

Predictions from a gls Object
needUpdate

Check if Update is Needed
summary.pdMat

Summarize a pdMat Object
print.summary.pdMat

Print a summary.pdMat Object
fdHess

Finite difference Hessian
plot.nmGroupedData

Plot an nmGroupedData Object
Matrix

Assign Matrix Values
summary.modelStruct

Summarize a modelStruct Object
corExp

Exponential Correlation Structure
varClasses

Variance Function Classes
model.matrix.reStruct

reStruct Model Matrix
getGroups.lmList

Extract lmList Object Groups
varExp

Exponential Variance Function
varPower

Power Variance Function
varWeights.glsStruct

Variance Weights for glsStruct Object
ranef.lmList

Extract lmList Random Effects
corARMA

ARMA(p,q) Correlation Structure
nlmeObject

Fitted nlme Object
getGroups.varFunc

Extract varFunc Groups
corCompSymm

Compound Symmetry Correlation Structure
pdIdent

Multiple of the Identity Positive-Definite Matrix
logLik.varFunc

Extract varFunc logLik
getResponseFormula

Extract Formula Specifying Response Variable
asOneFormula

Combine Formulas of a Set of Objects
plot.lme

Plot an lme or nls object
needUpdate.modelStruct

Check if a modelStruct Object Needs Updating
coef.corStruct

Coefficients of a corStruct Object
corSpatial

Spatial Correlation Structure
summary.lmList

Summarize an lmList Object
corMatrix.corStruct

Matrix of a corStruct Object
gnlsControl

Control Values for gnls Fit
residuals.lmeStruct

Calculate lmeStruct Residuals
summary.corStruct

Summarize a corStruct Object
fixef.lmList

Extract lmList Fixed Effects
Initialize.corStruct

Initialize corStruct Object
lme

Linear Mixed-Effects Models
pooledSD

Extract Pooled Standard Deviation
coef.lme

Extract lme Coefficients
logLik.corStruct

Extract corStruct Log-Likelihood
lmeScale

Scale for lme Optimization
plot.ranef.lmList

Plot a ranef.lmList Object
logDet.pdMat

Extract Log-Determinant from a pdMat Object
Names.pdMat

Names of a pdMat Object
update.varFunc

Update varFunc Object
ACF.gls

Autocorrelation Function for gls Residuals
summary.varFunc

Summarize varFunc Object
pdNatural

General Positive-Definite Matrix in Natural Parametrization
LDEsysMat

Generate system matrix for LDEs
pdMat

Positive-Definite Matrix
Matrix.reStruct

Assign reStruct Matrices
predict.lme

Predictions from an lme Object
residuals.nlmeStruct

Calculate nlmeStruct Residuals
Dim.corSpatial

Dimensions of a corSpatial Object
intervals.gls

Confidence Intervals on gls Parameters
corLin

Linear Correlation Structure
recalc.modelStruct

Recalculate for a modelStruct Object
getVarCov

Extract variance-covariance matrix
pdConstruct

Construct pdMat Objects
corGaus

Gaussian Correlation Structure
qqnorm.lme

Normal Plot of Residuals or Random Effects from an lme Object
glsObject

Fitted gls Object
Dim

Extract Dimensions from an Object
nlsList

List of nls Objects with a Common Model
summary.lme

Summarize an lme Object
plot.gls

Plot a gls Object
varFunc

Variance Function Structure
corCAR1

Continuous AR(1) Correlation Structure
getData.lme

Extract lme Object Data
Variogram.default

Calculate Semi-variogram
gsummary

Summarize by Groups
plot.ranef.lme

Plot a ranef.lme Object
varConstPower

Constant Plus Power Variance Function
logLik.lme

Log-Likelihood of an lme Object
plot.Variogram

Plot a Variogram Object
intervals

Confidence Intervals on Coefficients
anova.lme

Compare Likelihoods of Fitted Objects
pdDiag

Diagonal Positive-Definite Matrix
pdClasses

Positive-Definite Matrix Classes
lmList

List of lm Objects with a Common Model
getGroups.lme

Extract lme Object Groups
summary.nlsList

Summarize an nlsList Object
lme.lmList

LME fit from lmList Object
pdLogChol

General Positive-Definite Matrix
pdBlocked

Positive-Definite Block Diagonal Matrix
qqnorm.gls

Normal Plot of Residuals from a gls Object
plot.intervals.lmList

Plot lmList Confidence Intervals
collapse.groupedData

Collapse a groupedData Object
lmeStruct

Linear Mixed-Effects Structure
corSpher

Spherical Correlation Structure
residuals.gnlsStruct

Calculate gnlsStruct Residuals
coef.lmList

Extract lmList Coefficients
Initialize.varFunc

Initialize varFunc Object
simulate.lme

Simulate results from lme models
varComb

Combination of Variance Functions
corMatrix

Extract Correlation Matrix
glsStruct

Generalized Least Squares Structure
pdSymm

General Positive-Definite Matrix
isInitialized

Check if Object is Initialized
plot.nffGroupedData

Plot an nffGroupedData Object
nlmeControl

Control Values for nlme Fit
lmList.groupedData

lmList Fit from a groupedData Object
isBalanced

Check a Design for Balance
splitFormula

Split a Formula
plot.lmList

Plot an lmList Object
nlme.nlsList

NLME fit from nlsList Object
residuals.glsStruct

Calculate glsStruct Residuals
reStruct

Random Effects Structure
lme.groupedData

LME fit from groupedData Object
logLik.gnls

Log-Likelihood of a gnls Object
gls

Fit Linear Model Using Generalized Least Squares
plot.nfnGroupedData

Plot an nfnGroupedData Object
Variogram.corGaus

Calculate Semi-variogram for a corGaus Object
Variogram.lme

Calculate Semi-variogram for Residuals from an lme Object
logDet.corStruct

Extract corStruct Log-Determinant
nlme

Nonlinear Mixed-Effects Models
pdFactor

Square-Root Factor of a Positive-Definite Matrix
predict.lmList

Predictions from an lmList Object
formula.pdBlocked

Extract pdBlocked Formula
getCovariate.corStruct

Extract corStruct Object Covariate
coef.reStruct

reStruct Object Coefficients
ranef.lme

Extract lme Random Effects
anova.gls

Compare Likelihoods of Fitted Objects
lmeControl

Control Values for lme Fit
corAR1

AR(1) Correlation Structure
Variogram.corSpatial

Calculate Semi-variogram for a corSpatial Object
plot.compareFits

Plot a compareFits Object
glsControl

Control Values for gls Fit
gnlsObject

Fitted gnls Object
gnls

Fit Nonlinear Model Using Generalized Least Squares
groupedData

Construct a groupedData Object
gapply

Apply a Function by Groups
Cefamandole

Pharmacokinetics of Cefamandole
MathAchSchool

School demographic data for MathAchieve
Machines

Productivity Scores for Machines and Workers
Quinidine

Quinidine Kinetics
Gasoline

Refinery yield of gasoline
Wheat

Yields by growing conditions
Glucose2

Glucose Levels Following Alcohol Ingestion
Glucose

Glucose levels over time
Oxide

Variability in Semiconductor Manufacturing
Muscle

Contraction of heart muscle sections
Fatigue

Cracks caused by metal fatigue
Alfalfa

Split-Plot Experiment on Varieties of Alfalfa
IGF

Radioimmunoassay of IGF-I Protein
Soybean

Growth of soybean plants
Earthquake

Earthquake Intensity
Phenobarb

Phenobarbitol Kinetics
Spruce

Growth of Spruce Trees
Meat

Tenderness of meat
Nitrendipene

Assay of nitrendipene
Tetracycline1

Pharmacokinetics of tetracycline
PBG

Effect of Phenylbiguanide on Blood Pressure
bdf

Language scores
Oats

Split-plot Experiment on Varieties of Oats
Rail

Evaluation of Stress in Railway Rails
Pixel

X-ray pixel intensities over time
MathAchieve

Mathematics achievement scores
Tetracycline2

Pharmacokinetics of tetracycline
RatPupWeight

The weight of rat pups
Oxboys

Heights of Boys in Oxford
ergoStool

Ergometrics experiment with stool types
Orthodont

Growth curve data on an orthdontic measurement
Relaxin

Assay for Relaxin
Wheat2

Wheat Yield Trials
BodyWeight

Rat weight over time for different diets
Ovary

Counts of Ovarian Follicles
Dialyzer

High-Flux Hemodialyzer
Wafer

Modeling of Analog MOS Circuits
Milk

Protein content of cows' milk
Remifentanil

Pharmacokinetics of remifentanil
Gun

Methods for firing naval guns
Assay

Bioassay on Cell Culture Plate