Bolus_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
instant.stan.extension.
Augmented Prediction for nlmixr fit
Extract the Nlmixr bound information from a function.
Print x using the message facility
Convert fit to FOCEi style fit
Simulate a nlmixr solved system
Return composite nlme/focei to nlme
Fit a non-population dynamic model
Fit a non-population dynamic model using mcmc
Messages the nlmixr logo...
concentrations from a linear compartment model
Inverse Guassian absorption model
Predict a nlmixr solved system
2 Compartment Model
Create the nlme specs list for nlmixr nlme solving
Generate SAEM initial estimates for THETA.
2 Compartment Model with Michelis Menton Clearance
Get model$log.eta for SAEM
Return composite saem/focei to saem
Infusion_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
Plot a focei.fit plot
Bootstrap data
Plot an SAEM model fit
Get the likelihood for ETA
Pregnant Rat Diet Experiment
Get the Function pointers for the LBJ'S routine
Objects exported from other packages
Get the variance for the nlme fit process based on UI
Get the SAEM model$res.mod code
Calculate gnlmm variance-covariance matrix of fixed effects
Extract the fitted values from the model
Oral_1CPT -- 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Get error names for SAEM
Construct RxODE linCmt function
Configure an SAEM model
Get the FOCEi theta or eta specification for model.
Collect warnings and just warn once.
Fit a nlmixr model
Dispaly nlmixr's version
Calculate the Gradient for an individual
Generate an SAEM model
Solve the FOCEI inner problem
Get saem initilization list
Calculate gnlmm variance-covariance matrix of random effects
Vpc function for nlmixr
Get the Hessian for the environment
SAEM's init$omega
Update ETAs based on d(eta)/d(theta)
Parent/Metabolite dataset
Visual predictive check (VPC) for nlmixr nlme objects
Forward covariate selection for nlme-base non-linear mixed effect models
Find the assignments in R expression
Extract the number of observations for the focei fit
Access the model list information for nlmixr's nlme user functions
Convert NONMEM/Monolix data to RxODE/nlmixr style data
Get ETA names
Sets nodes and weigts of Gauss-Hermite quadrature
Parameter history extraction
Parameters for a linear compartment model for SAEM
Extract log likelihood for focei fit
nlmixrBounds.focei.upper.lower
Get upper/lower/names for THETAs
Extract residuals from the FOCEI fit
FOCEI ETA setup,
Fit nlme-based mixed-effect model using ODE implementation
FOCEI THETA setup,
Returns the gradient for FOCEi environment
Summary of a non-population dynamic model fit using mcmc
Get initial estimate for ares SAEM.
nlmixr fits population PK and PKPD non-linear mixed effects models.
Create the nlme parameter transform function from the UI object.
Print an SAEM model fit summary
Get the eta->eta.trans for SAEM
Build linear solved information based on defined parameters.
Get initial estimate for bres SAEM.
Return RxODE model with predictions appended
Validate nlmixr
Generate saem.fit user function.
Get THETA names for nlmixr's SAEM
Summary of a non-population dynamic model fit using mcmc
Print a focei fit
Get the Parameter function with THETA/ETAs defined
Plot of a non-population dynamic model fit
Print a gnlmm fit
Print UI function
Cleanup saem_fit environment by removing dll after the object is no logner used by R.
Summary of a non-population dynamic model fit
Control Options for SAEM
Plot of a non-population dynamic model fit using mcmc
Fit an SAEM model
Multiple dose Theophiline PK data
Multiple dose Theophiline PK data
Produce trace-plot for fit if applicable
Extract variance/covariance matrix for FOCEI fit
Get the likelihood slope for ETA
RxODE_focei_finalize_llik
Finalize likelihood environment
Convert focei fit to a data.frame
Fit nlme-based linear compartment mixed-effect model using closed form solution
GOF plots for nlme-based mixed-effect models
Convert/Format the data appropriately for nlmixr
Simulated Data Set for comparing objective functions
Prepares the UI function and returns a list.
Clear memoise cache for nlmixr
Get the FOCEi initilizations
Generate SAEM model list
Nelder-Mead of simplex search
nlmixrUI.saem.model.omega
Get the SAEM model Omega
Get a list of directories for inclusion
Prediction after a gnlmm fit
Pump failure example dataset
Print an SAEM model fit summary
Get -LLIK for individual
Get -Grad for individual
Print a non-population dynamic model fit object
VPC for nlmixr saemFit objects
VPC based on ui model
1 Compartment Model w/ Michelis Menton Elimination
Fit a generalized nonlinear mixed-effect model
FOCEI Fit for nlmixr
Get the FOCEi theta specification for the model