Return VarCorr for nlmixr nlme
2 Compartment Model
NPDE calculation for nlmixr
Oral_1CPT -- 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
Calculate gnlmm variance-covariance matrix of fixed effects
Covariance matrix by Fisher Information Matrix via linearization
Change a nlmixr fit object to a huxtable
Return composite saem/focei to saem
Bootstrap data
This gets the parsed data in the lower-level manner that nlmixr expects.
Fit a non-population dynamic model
Log-likelihood using Gaussian Quadrature
Fit/Evaulate FOCEi
FOCEi fit
Parameters for a linear compartment model for SAEM
concentrations from a linear compartment model
Return composite nlme/focei to nlme
Fit a non-population dynamic model using mcmc
Convert fit to FOCEi style fit
Get the FOCEi theta or eta specification for model.
Cox Box transformation
Generalized Cholesky Matrix Decomposition
Construct RxODE linCmt function
instant.stan.extension.
Configure an SAEM model
Access the model list information for nlmixr's nlme user functions
Get the FOCEi theta specification for the model
Get parameters that are fixed
Get the FOCEi initializations
GOF plots for nlme-based mixed-effect models
Inverse Guassian absorption model
Get initial estimate for ares SAEM.
Get THETA names for nlmixr's SAEM
Validate nlmixr
Get initial estimate for bres SAEM.
Get the Parameter function with THETA/ETAs defined
Control Options for FOCEi
Forward covariate selection for nlme-base non-linear mixed effect models
Sets nodes and weigts of Gauss-Hermite quadrature
Fit a generalized nonlinear mixed-effect model
nlmixr ini block handling
nlmixr fits population PK and PKPD non-linear mixed effects models.
Dispaly nlmixr's version
Plot of a non-population dynamic model fit using mcmc
Plot a nlmixr data object
Extract the Nlmixr bound information from a function.
Get ETA names
Predict a nlmixr solved system
Generate an SAEM model
Calculate gnlmm variance-covariance matrix of random effects
Augmented Prediction for nlmixr fit
nlmixrBounds.focei.upper.lower
Get upper/lower/names for THETAs
Generate saem.fit user function.
Get parameters that are fixed for SAEM
Print an SAEM model fit summary
Create the nlme specs list for nlmixr nlme solving
Parent/Metabolite dataset
Print x using the message facility
Pump failure example dataset
Convert/Format the data appropriately for nlmixr
Generate SAEM model list
nlmixr model block
nlmixrUI.saem.model.omega
Get the SAEM model Omega
Get saem initilization list
Return the objective function
Get a list of directories for inclusion
Get the variance for the nlme fit process based on UI
Print a gnlmm fit
SAEM's init$omega
Produce trace-plot for fit if applicable
Vpc function for nlmixr
Find the assignments in R expression
Plot an SAEM model fit
Fit a nlmixr model
Print UI function
Set Objective function type for a nlmixr object
Fit nlme-based linear compartment mixed-effect model using closed form solution
Clear memoise cache for nlmixr
Messages the nlmixr logo...
Create the nlme parameter transform function from the UI object.
Fit nlme-based mixed-effect model using ODE implementation
Create a large output based on a nlmixr fit
Get model$log.eta for SAEM
Return RxODE model with predictions appended
Return the square root of general square matrix A
Generate SAEM initial estimates for THETA.
Prediction after a gnlmm fit
Summary of a non-population dynamic model fit using mcmc
Summary of a non-population dynamic model fit
Print a non-population dynamic model fit object
Nelder-Mead of simplex search
Simulate a nlmixr solved system
Prepares the UI function and returns a list.
Get error names for SAEM
Convert data to RxODE format (depreciated)
nlmixrUI.saem.distribution
Get SAEM distribution
Get the SAEM model$res.mod code
Visual predictive check (VPC) for nlmixr nlme objects
Get the eta->eta.trans for SAEM
Cleanup saem_fit environment by removing dll after the object is no logner used by R.
Extract residuals from the FOCEI fit
Summary of a non-population dynamic model fit using mcmc
Create a run summary word document
Pregnant Rat Diet Experiment
Multiple dose Theophiline PK data
Objects exported from other packages
Warfarin PK/PD data
Multiple dose Theophiline PK data
VPC based on ui model
Yeo-Johnson Transformation
VPC for nlmixr saemFit objects
Single Dose Phenobarbitol PK/PD
Control Options for SAEM
Plot of a non-population dynamic model fit
Fit an SAEM model
Output table/data.frame options
Print an SAEM model fit summary
Simulated Data Set for comparing objective functions
Infusion_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
Add CWRES
1 Compartment Model w/ Michelis Menton Elimination
Bolus_1CPT -- 1 Compartment Model Simulated Data from ACOP 2016
2 Compartment Model with Michelis Menton Clearance