nlmixr (version 1.1.1-2)

addNpde: NPDE calculation for nlmixr

Description

NPDE calculation for nlmixr

Usage

addNpde(object, nsim = 300, ties = TRUE, seed = 1009,
  updateObject = TRUE, cholSEtol = (.Machine$double.eps)^(1/3), ...)

Arguments

object

nlmixr fit object

nsim

Number of simulations. By default this is 300

ties

When TRUE, the npde distribution can have ties. When FALSE, the npde distribution uses uniform random numbers to prevent ties.

seed

Seed for running nlmixr simulation. By default 1009

updateObject

Boolean indicating if original object should be updated. By default this is TRUE.

cholSEtol

tolerance for Generalized Cholesky Decomposition. Defaults to suggested (.Machine$double.eps)^(1/3)

...

Other ignored parameters.

Value

New nlmixr fit object