print.getPPKinits

Prints a summary of the results from the initial parameter estimation pipeline,
including recommended initial estimates, ETA variance estimates, and parameter descriptions.
It is the default S3 <code>print</code> method for objects of class <code>getPPKinits</code>.

Provides automated methods for generating initial parameter estimates
in population pharmacokinetic modeling. The pipeline integrates adaptive single-point
methods, naive pooled graphic approaches, noncompartmental analysis methods, and parameter
sweeping across pharmacokinetic models. It estimates residual unexplained variability
using either data-driven or fixed-fraction approaches and assigns pragmatic initial values
for inter-individual variability. These strategies are designed to improve model
robustness and convergence in 'nlmixr2' workflows. For more details see
Huang Z, Fidler M, Lan M, Cheng IL, Kloprogge F, Standing JF (2025)
<doi:10.1007/s10928-025-10000-z>.

Zhonghui Huang

nlmixr2autoinit

Automatic Generation of Initial Estimates for Population
Pharmacokinetic Modeling

Joseph Standing

Matthew Fidler

Frank Kloprogge

print.getPPKinits function

<dl><dt>x</dt>
<dd>An object of class <code>getPPKinits</code> containing the initial parameter estimation results.
Expected components include:<ul>
<li><code>Recommended_initial_estimates</code>: A data frame with estimated values and selection methods.</li>
<li><code>Parameter.descriptions</code>: A character vector explaining the meaning of each parameter.</li>
<li><code>time.spent</code>: Time taken to compute the estimates.</li>
</ul></dd>
<dt>...</dt>
<dd>Additional arguments (for compatibility with the generic <code><a href="/link/print()?package=nlmixr2autoinit&version=1.0.0" data-mini-rdoc="nlmixr2autoinit::print()">print()</a></code>).</dd></dl>

Arguments

Print method for getPPKinits objects — print.getPPKinits

<dl>

<dt>x</dt>
<dd>An object of class <code>getPPKinits</code> containing the initial parameter estimation results.
Expected components include:<ul>
<li><code>Recommended_initial_estimates</code>: A data frame with estimated values and selection methods.</li>
<li><code>Parameter.descriptions</code>: A character vector explaining the meaning of each parameter.</li>
<li><code>time.spent</code>: Time taken to compute the estimates.</li>
</ul></dd>


<dt>...</dt>
<dd>Additional arguments (for compatibility with the generic <code><a href='https://rdrr.io/r/base/print.html'>print()</a></code>).</dd>

</dl>

print.getPPKinits: Print method for `getPPKinits` objects

Description

Usage

Value

Arguments

Examples