.nlmixrOptimFunC

.nlmixrOptimGradC

A surrogate function for optim to call for ode solving

internal

Fit and compare nonlinear mixed-effects models in
differential equations with flexible dosing information commonly seen
in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
solving is by compiled C code provided in the 'rxode2' package (Wang,
Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Matthew Fidler

nlmixr2est

Nonlinear Mixed Effects Models in Population PK/PD, Estimation
Routines

Yuan Xiong

Rik Schoemaker

Justin Wilkins

Wenping Wang

Robert Leary

Mason McComb

Vipul Mann

Mirjam Trame

Mahmoud Abdelwahab

Teun Post

Richard Hooijmaijers

Hadley Wickham

Dirk Eddelbuettel

Johannes Pfeifer

Robert B. Schnabel

Elizabeth Eskow

Emmanuelle Comets

Audrey Lavenu

Marc Lavielle

David Ardia

Katharine Mullen

Ben Goodrich

.nlmixrOptimFunC function

<dl><dt>pars</dt>
<dd>Parameters that will be estimated</dd></dl>

Arguments

Author

A surrogate function for optim to call for ode solving — .nlmixrOptimFunC

<dl>

<dt>pars</dt>
<dd>Parameters that will be estimated</dd>

</dl>

A surrogate function for optim to call for ode solving

.nlmixrOptimFunC: A surrogate function for optim to call for ode solving

Description

Usage

Value

Arguments

Author

Details