dat2_time_to_posix

Combine "YYYY-MM-DD" and "HH:MM" character vectors into POSIXct.

This shows how NONMEM(R) software works. NONMEM's classical
estimation methods like 'First Order(FO) approximation', 'First Order
Conditional Estimation(FOCE)', and 'Laplacian approximation' are explained.
Additionally, provides functions for post-run processing of NONMEM output
files, generating comprehensive PDF diagnostic reports including objective
function value analysis, parameter estimates, prediction diagnostics,
residual diagnostics, empirical Bayes estimate (EBE) analysis, input data
summary, and individual pharmacokinetic parameter distributions.

Kyun-Seop Bae

Understanding Nonlinear Mixed Effects Modeling for Population
Pharmacokinetics

dat2_time_to_posix function

<dl><dt>dat2</dt>
<dd>character vector of dates in "YYYY-MM-DD" format.</dd>
<dt>time</dt>
<dd>character vector of times in "HH:MM" format.</dd>
<dt>tz</dt>
<dd>time zone. Default "UTC".</dd></dl>

Arguments

Combine Date and Time Strings into POSIXct — dat2_time_to_posix

<dl>

<dt>dat2</dt>
<dd>character vector of dates in "YYYY-MM-DD" format.</dd>


<dt>time</dt>
<dd>character vector of times in "HH:MM" format.</dd>


<dt>tz</dt>
<dd>time zone. Default "UTC".</dd>

</dl>

dat2_time_to_posix: Combine Date and Time Strings into POSIXct

Description

Usage

Value

Arguments