TrialDesignOptimalConditionalError

<p>A class for a trial design object using the optimal conditional error function.</p>

Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.

Morten Dreher

optconerrf

Optimal Monotone Conditional Error Functions

Werner Brannath

Cornelia Ursula Kunz

Johanna zur Verth

TrialDesignOptimalConditionalError function

Optimal Conditional Error Design — TrialDesignOptimalConditionalError

Optimal Conditional Error Design

TrialDesignOptimalConditionalError: Optimal Conditional Error Design

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