pROC (version 1.18.0)

# auc: Compute the area under the ROC curve

## Description

This function computes the numeric value of area under the ROC curve (AUC) with the trapezoidal rule. Two syntaxes are possible: one object of class “roc”, or either two vectors (response, predictor) or a formula (response~predictor) as in the roc function. By default, the total AUC is computed, but a portion of the ROC curve can be specified with partial.auc.

## Usage

auc(...)
# S3 method for roc
auc(roc, partial.auc=FALSE, partial.auc.focus=c("specificity",
"sensitivity"), partial.auc.correct=FALSE,
allow.invalid.partial.auc.correct = FALSE, ...)
# S3 method for smooth.roc
auc(smooth.roc, ...)
# S3 method for multiclass.roc
auc(multiclass.roc, ...)
# S3 method for formula
auc(formula, data, ...)
# S3 method for default
auc(response, predictor, ...)

## Arguments

roc, smooth.roc, multiclass.roc

a “roc” object from the roc function, a “smooth.roc” object from the smooth function, or a “multiclass.roc” or “mv.multiclass.roc” from the multiclass.roc function.

response, predictor

arguments for the roc function.

formula, data

a formula (and possibly a data object) of type response~predictor for the roc function.

partial.auc

either FALSE (default: consider total area) or a numeric vector of length 2: boundaries of the AUC to consider in [0,1] (or [0,100] if percent is TRUE).

partial.auc.focus

if partial.auc is not FALSE and a partial AUC is computed, specifies if partial.auc specifies the bounds in terms of specificity (default) or sensitivity. Can be shortened to spec/sens or even sp/se. Ignored if partial.auc=FALSE.

partial.auc.correct

logical indicating if the correction of AUC must be applied in order to have a maximal AUC of 1.0 and a non-discriminant AUC of 0.5 whatever the partial.auc defined. Ignored if partial.auc=FALSE. Default: FALSE.

allow.invalid.partial.auc.correct

logical indicating if the correction must return NA (with a warning) when attempting to correct a pAUC below the diagonal. Set to TRUE to return a (probably invalid) corrected AUC. This is useful especially to avoid introducing a bias against low pAUCs in bootstrap operations.

further arguments passed to or from other methods, especially arguments for roc when calling auc.default, auc.formula, auc.smooth.roc. Note that the auc argument of roc is not allowed. Unused in auc.roc.

## Value

The numeric AUC value, of class c("auc", "numeric") (or c("multiclass.auc", "numeric") or c("mv.multiclass.auc", "numeric") if a “multiclass.roc” was supplied), in fraction of the area or in percent if percent=TRUE, with the following attributes:

partial.auc

if the AUC is full (FALSE) or partial (and in this case the bounds), as defined in argument.

partial.auc.focus

only for a partial AUC, if the bound specifies the sensitivity or specificity, as defined in argument.

partial.auc.correct

only for a partial AUC, was it corrected? As defined in argument.

percent

whether the AUC is given in percent or fraction.

roc

the original ROC curve, as a “roc”, “smooth.roc” or “multiclass.roc” object.

## Smoothed ROC curves

There is no difference in the computation of the area under a smoothed ROC curve, except for curves smoothed with method="binomial". In this case and only if a full AUC is requested, the classical binormal AUC formula is applied:

$$auc=\phi\frac{a}{\sqrt{1 + b^2}}.$$

If the ROC curve is smoothed with any other method or if a partial AUC is requested, the empirical AUC described in the previous section is applied.

## Multi-class AUCs

With an object of class “multiclass.roc”, a multi-class AUC is computed as an average AUC as defined by Hand and Till (equation 7).

$$auc=\frac{2}{c(c-1)}\sum{aucs}$$

with aucs all the pairwise roc curves.

## Details

This function is typically called from roc when auc=TRUE (default). It is also used by ci. When it is called with two vectors (response, predictor) or a formula (response~predictor) arguments, the roc function is called and only the AUC is returned.

By default the total area under the curve is computed, but a partial AUC (pAUC) can be specified with the partial.auc argument. It specifies the bounds of specificity or sensitivity (depending on partial.auc.focus) between which the AUC will be computed. As it specifies specificities or sensitivities, you must adapt it in relation to the 'percent' specification (see details in roc).

partial.auc.focus is ignored if partial.auc=FALSE (default). If a partial AUC is computed, partial.auc.focus specifies if the bounds specified in partial.auc must be interpreted as sensitivity or specificity. Any other value will produce an error. It is recommended to plot the ROC curve with auc.polygon=TRUE in order to make sure the specification is correct.

If a pAUC is defined, it can be standardized (corrected). This correction is controled by the partial.auc.correct argument. If partial.auc.correct=TRUE, the correction by McClish will be applied:

$$\frac{1+\frac{auc-min}{max-min}}{2}$$

where auc is the uncorrected pAUC computed in the region defined by partial.auc, min is the value of the non-discriminant AUC (with an AUC of 0.5 or 50 in the region and max is the maximum possible AUC in the region. With this correction, the AUC will be 0.5 if non discriminant and 1.0 if maximal, whatever the region defined. This correction is fully compatible with percent.

Note that this correction is undefined for curves below the diagonal (auc < min). Attempting to correct such an AUC will return NA with a warning.

## References

Tom Fawcett (2006) An introduction to ROC analysis''. Pattern Recognition Letters 27, 861--874. DOI: 10.1016/j.patrec.2005.10.010.

David J. Hand and Robert J. Till (2001). A Simple Generalisation of the Area Under the ROC Curve for Multiple Class Classification Problems. Machine Learning 45(2), p. 171--186. DOI: 10.1023/A:1010920819831.

Donna Katzman McClish (1989) Analyzing a Portion of the ROC Curve''. Medical Decision Making 9(3), 190--195. DOI: 10.1177/0272989X8900900307.

Xavier Robin, Natacha Turck, Alexandre Hainard, et al. (2011) pROC: an open-source package for R and S+ to analyze and compare ROC curves''. BMC Bioinformatics, 7, 77. DOI: 10.1186/1471-2105-12-77.

roc, ci.auc

## Examples

# NOT RUN {
# Create a ROC curve:
data(aSAH)
roc.s100b <- roc(aSAH$outcome, aSAH$s100b)

# Get the full AUC
auc(roc.s100b)

# Get the partial AUC:
auc(roc.s100b, partial.auc=c(1, .8), partial.auc.focus="se", partial.auc.correct=TRUE)

# }