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paramlink (version 0.3-1)

Parametric linkage analysis

Description

Parametric pedigree analysis based on the Elston-Stewart algorithm. Singlepoint LOD scores and power analysis for diallelic markers. Also includes functions for manipulating and plotting pedigrees and linkage results.

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Version

Install

install.packages('paramlink')

Monthly Downloads

293

Version

0.3-1

License

GPL (>= 2)

Maintainer

Magnus Dehli Vigeland

Last Published

October 15th, 2011

Functions in paramlink (0.3-1)

linkres

S3 methods for class 'linkres'.

read.linkdat

Read/write 'linkdat' objects

genoDistr

Genotype probability distribution

likelihood

Pedigree likelihood

dominant

Example pedigree for linkage analysis: 23 individuals, 650 SNPs

toyped

Toy pedigree for linkage analysis

modifyPedigree

Modify the pedigree of 'linkdat' objects

linkdat.utils

linkdat utilities

markers

Marker genotypes for linkdat objects

setSim

Simulation vector for 'linkdat' objects

randomPed

Random pedigree

Xped

Example pedigree with X-linked disease pattern.

linkage.power

Power of a linkage study

SNPsim

Simulate SNP markers

setModel

Set, change or display the model parameters for 'linkdat' objects

Create simple pedigrees

plot.linkdat

Plot pedigrees with genotypes