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pathfindR (version 2.5.0)

get_gene_sets_list: Retrieve Organism-specific Gene Sets List

Description

Retrieve Organism-specific Gene Sets List

Usage

get_gene_sets_list(
  source = "KEGG",
  org_code = "hsa",
  species = "Homo sapiens",
  db_species = "HS",
  collection,
  subcollection = NULL
)

Value

A list containing 2 elements:

  • gene_sets - A list containing the genes involved in each gene set

  • descriptions - A named vector containing the descriptions for each gene set

. For 'KEGG' and 'MSigDB', it is possible to choose a specific organism. For a full list of all available KEGG organisms, see https://www.genome.jp/kegg/catalog/org_list.html. See msigdbr_species for all the species available in the msigdbr package used for obtaining 'MSigDB' gene sets. For Reactome, there is only one collection of pathway gene sets.

Arguments

source

As of this version, either 'KEGG', 'Reactome' or 'MSigDB' (default = 'KEGG')

org_code

(Used for 'KEGG' only) KEGG organism code for the selected organism. For a full list of all available organisms, see https://www.genome.jp/kegg/catalog/org_list.html

species

species name for output genes, such as Homo sapiens, Mus musculus, etc. See msigdbr_species for all the species available in the msigdbr package.

db_species

Species abbreviation for the human or mouse databases ("HS" or "MM").

collection

collection. e.g., H, C1. (default = NULL, i.e. list all gene sets in collection). See msigdbr_collections for all available options the msigdbr package.

subcollection

sub-collection, such as CGP, BP, etc. (default = NULL, i.e. list all gene sets in collection). See msigdbr_collections for all available options the msigdbr package.