final_character

<p>final_character, a potential marker for cancer prognostic and immunotherapy, generated by 'get_final_signature'</p>

datasets

A systematic bioinformatics tool to develop a new pathway-based gene panel for tumor mutational burden (TMB) assessment (pathway-based tumor mutational burden, PTMB), using somatic mutations files in an efficient manner from either The Cancer Genome Atlas sources or any in-house studies as long as the data is in mutation annotation file (MAF) format. Besides, we develop a multiple machine learning method using the sample's PTMB profiles to identify cancer-specific dysfunction pathways, which can be a biomarker of prognostic and predictive for cancer immunotherapy.

Junwei Han

pathwayTMB

Pathway Based Tumor Mutational Burden

Xiangmei Li

final_character function

<p>An object of class <code>character</code> of length 2.</p>

final_character: final_character, the example's final signature

Description

Usage

Arguments

Format