plot.SimPRMD

other arguments ignored (for compatibility with generic)

controls whether there is a title on plots or not.

title.add

Plot the predictive probability of nTTP &lt; target toxicity for all cycles
and doses , the mean nTTP vs cycle1 and cycle &gt; 2 for all doses of a
SimPRMD object. Plot median treatment duration boxplot along with the DLT
drop off rate when implementing <code><a rd-options="" href="/link/SimPRMD?package=phase1PRMD&version=1.0.2" data-mini-rdoc="phase1PRMD::SimPRMD">SimPRMD</a></code> with option
<code>DLT.drop.flag = TRUE</code>.

Implements Bayesian phase I repeated measurement design that
accounts for multidimensional toxicity endpoints and longitudinal efficacy
measure from multiple treatment cycles. The package provides flags to
fit a variety of model-based phase I design, including 1 stage models with
or without individualized dose modification, 3-stage models with or without
individualized dose modification, etc. Functions are provided to recommend
dosage selection based on the data collected in the available patient cohorts
and to simulate trial characteristics given design parameters.
Yin, Jun, et al. (2017) <doi:10.1002/sim.7134>.

Lu Zhang

phase1PRMD

Personalized Repeated Measurement Design for Phase I Clinical
Trials

plot.SimPRMD function

Plot the predictive probability of nTTP &lt; target toxicity for all cycles
and doses , the mean nTTP vs cycle1 and cycle &gt; 2 for all doses of a
SimPRMD object. Plot median treatment duration boxplot along with the DLT
drop off rate when implementing <code><a rd-options='' href='SimPRMD'>SimPRMD</a></code> with option
<code>DLT.drop.flag = TRUE</code>.

plot.SimPRMD: Plots of a SimPRMD object

Description

Usage

Arguments

Examples