eff_dat

<p>This data set provides the efficacy data from 22 patients.</p>

datasets

Implements our Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints from multiple treatment cycles. The package also provides a novel design to account for both multidimensional toxicity endpoints and early-stage efficacy endpoints in the phase I design. For both designs, functions are provided to recommend the next dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) <doi:10.1002/sim.7134>.

Jun Yin

phase1RMD

Repeated Measurement Design for Phase I Clinical Trial

eff_dat function

<p>A matrix containing 22 observations.</p>

eff_dat: Patient efficacy data

Description

Usage

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References