sumstats_munged_example_input

Example munged dataframe - refer to ldscr R package (https://github.com/mglev1n/ldscr)

Provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 <doi:10.1038/ng.3406>) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates.

Yujie Zhao

pleioh2g

Estimation of Pleiotropic Heritability from Genome-Wide
Association Studies (GWAS) Summary Statistics

sumstats_munged_example_input function

<dl><dt>example</dt>
<dd>(character) "401.1" which have been included as example traits.</dd>
<dt>dataframe</dt>
<dd>(logical) If `TRUE` (default), return an example munged dataframe. If `FALSE`, return path to the file on disk.</dd></dl>

Arguments

Example munged dataframe - refer to ldscr R package (https://github.com/mglev1n/ldscr) — sumstats_munged_example_input

<dl>

<dt>example</dt>
<dd>(character) "401.1" which have been included as example traits.</dd>


<dt>dataframe</dt>
<dd>(logical) If `TRUE` (default), return an example munged dataframe. If `FALSE`, return path to the file on disk.</dd>

</dl>

sumstats_munged_example_input: Example munged dataframe - refer to ldscr R package (https://github.com/mglev1n/ldscr)

Description

Usage

Value

Arguments