This function applies the zrollup method to a pepData object for each unique protein and returns a proData object.
zrollup(pepData, combine_fn, parallel = TRUE)
an omicsData object of class 'proData'
an omicsData object of class 'pepData'
logical indicating what combine_fn to use, defaults to median, other option is mean
logical indicating whether or not to use "doParallel" loop in applying zrollup function. Defaults to TRUE.
In the zrollup method, peptides are scaled as, pep_scaled = (pep - median)/sd, and protein abundance is set as the mean of these scaled peptides.
Polpitiya, A. D., Qian, W.-J., Jaitly, N., Petyuk, V. A., Adkins, J. N., Camp, D. G., ... Smith, R. D. (2008). DAnTE: a statistical tool for quantitative analysis of -omics data. Bioinformatics (Oxford, England), 24(13), 1556-1558.