run_mlx

An easy-to-use tool for implementing Neural Ordinary Differential Equations (NODEs) in pharmacometric software such as 'Monolix', 'NONMEM', and 'nlmixr2', see Bräm et al. (2024) <doi:10.1007/s10928-023-09886-4> and Bräm et al. (2025) <doi:10.1002/psp4.13265>. The main functionality is to automatically generate structural model code describing computations within a neural network. Additionally, parameters and software settings can be initialized automatically. For using these additional functionalities with 'Monolix', 'pmxNODE' interfaces with 'MonolixSuite' via the 'lixoftConnectors' package. The 'lixoftConnectors' package is distributed with 'MonolixSuite' (<https://monolixsuite.slp-software.com/r-functions/2024R1/package-lixoftconnectors>) and is not available from public repositories.

Dominic Bräm

pmxNODE

Application of NODEs in 'Monolix', 'NONMEM', and 'nlmixr2'

Bernhard Steiert

Gilbert Koch

Matthew Fidler

run_mlx function

<dl><dt>mlx_file</dt>
<dd>(string) Absolute or relative Path/Name of Monolix file to run. Must be in R-style, i.e., path must be with
slashes. File must be given with file extension, e.g., monolix_file.mlxtran</dd></dl>

Arguments

Author

Run Monolix from R — run_mlx

<dl>

<dt>mlx_file</dt>
<dd>(string) Absolute or relative Path/Name of Monolix file to run. Must be in R-style, i.e., path must be with
slashes. File must be given with file extension, e.g., monolix_file.mlxtran</dd>

</dl>

Run Monolix from R

run_mlx: Run Monolix from R

Description

Usage

Value

Arguments

Author

Details

Examples