Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given
times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero-
and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008)
<https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf>); parametric simulation from NONMEM-generated parameter estimates
and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

Justin Wilkins

pmxTools

Pharmacometric and Pharmacokinetic Toolkit

Bill Denney

Rik Schoemaker

Satyaprakash Nayak

Leonid Gibiansky

Andrew Hooker

E. Niclas Jonsson

Mats O. Karlsson

John Johnson

gm function

<dl><dt>x</dt>
<dd>Numeric vector.</dd>
<dt>na.rm</dt>
<dd>Flag for removing <code>NA</code> values (defaults to <code>FALSE</code>).</dd>
<dt>neg.rm</dt>
<dd>Flag for removing negative or zero values (defaults to <code>FALSE</code>).</dd></dl>

Arguments

Justin Wilkins, <a href="/link/justin.wilkins%40occams.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::justin.wilkins@occams.com">justin.wilkins@occams.com</a>

Author

Calculate geometric mean — gm

<dl>

<dt>x</dt>
<dd>Numeric vector.</dd>


<dt>na.rm</dt>
<dd>Flag for removing <code>NA</code> values (defaults to <code>FALSE</code>).</dd>


<dt>neg.rm</dt>
<dd>Flag for removing negative or zero values (defaults to <code>FALSE</code>).</dd>

</dl>

Justin Wilkins, <a href='mailto:justin.wilkins@occams.com'>justin.wilkins@occams.com</a>

gm: Calculate geometric mean

Description

Usage

Value

Arguments

Author

Examples