pmxTools

pmxTools-package

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand &amp; Mentre (2008) <a href="https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf">https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf</a>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

internal

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given
times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero-
and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008)
<https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf>); parametric simulation from NONMEM-generated parameter estimates
and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

Justin Wilkins

Pharmacometric and Pharmacokinetic Toolkit

Bill Denney

Rik Schoemaker

Satyaprakash Nayak

Leonid Gibiansky

Andrew Hooker

E. Niclas Jonsson

Mats O. Karlsson

John Johnson

pmxTools-package function

Maintainer: Justin Wilkins <a href="/link/justin.wilkins%40occams.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::justin.wilkins@occams.com">justin.wilkins@occams.com</a> (<a href="https://orcid.org/0000-0002-7099-9396">ORCID</a>)
Authors:<ul>
<li>Bill Denney <a href="/link/wdenney%40humanpredictions.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::wdenney@humanpredictions.com">wdenney@humanpredictions.com</a> (<a href="https://orcid.org/0000-0002-5759-428X">ORCID</a>)</li>
<li>Rik Schoemaker <a href="/link/rik.schoemaker%40occams.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::rik.schoemaker@occams.com">rik.schoemaker@occams.com</a></li>
</ul>Other contributors:<ul>
<li>Satyaprakash Nayak <a href="/link/sn248%40cornell.edu?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::sn248@cornell.edu">sn248@cornell.edu</a> [contributor]</li>
<li>Leonid Gibiansky <a href="/link/lgibiansky%40quantpharm.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::lgibiansky@quantpharm.com">lgibiansky@quantpharm.com</a> [contributor]</li>
<li>Andrew Hooker <a href="/link/Andrew.Hooker%40farmbio.uu.se?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::Andrew.Hooker@farmbio.uu.se">Andrew.Hooker@farmbio.uu.se</a> [contributor]</li>
<li>E. Niclas Jonsson <a href="/link/niclas.jonsson%40pharmetheus.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::niclas.jonsson@pharmetheus.com">niclas.jonsson@pharmetheus.com</a> [contributor]</li>
<li>Mats O. Karlsson <a href="/link/mats.karlsson%40farmbio.uu.se?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::mats.karlsson@farmbio.uu.se">mats.karlsson@farmbio.uu.se</a> [contributor]</li>
<li>John Johnson <a href="/link/johndjohnson%40gmail.com?package=pmxTools&version=1.5" data-mini-rdoc="pmxTools::johndjohnson@gmail.com">johndjohnson@gmail.com</a> [contributor]</li>
</ul>

Author

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand &amp; Mentre (2008) <a href='https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf'>https://www.facm.ucl.ac.be/cooperation/Vietnam/WBI-Vietnam-October-2011/Modelling/Monolix32_PKPD_library.pdf</a>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

pmxTools: Pharmacometric and Pharmacokinetic Toolkit — pmxTools-package

Maintainer: Justin Wilkins <a href='mailto:justin.wilkins@occams.com'>justin.wilkins@occams.com</a> (<a href='https://orcid.org/0000-0002-7099-9396'>ORCID</a>)
Authors:<ul>
<li>Bill Denney <a href='mailto:wdenney@humanpredictions.com'>wdenney@humanpredictions.com</a> (<a href='https://orcid.org/0000-0002-5759-428X'>ORCID</a>)</li>
<li>Rik Schoemaker <a href='mailto:rik.schoemaker@occams.com'>rik.schoemaker@occams.com</a></li>
</ul>

Other contributors:<ul>
<li>Satyaprakash Nayak <a href='mailto:sn248@cornell.edu'>sn248@cornell.edu</a> [contributor]</li>
<li>Leonid Gibiansky <a href='mailto:lgibiansky@quantpharm.com'>lgibiansky@quantpharm.com</a> [contributor]</li>
<li>Andrew Hooker <a href='mailto:Andrew.Hooker@farmbio.uu.se'>Andrew.Hooker@farmbio.uu.se</a> [contributor]</li>
<li>E. Niclas Jonsson <a href='mailto:niclas.jonsson@pharmetheus.com'>niclas.jonsson@pharmetheus.com</a> [contributor]</li>
<li>Mats O. Karlsson <a href='mailto:mats.karlsson@farmbio.uu.se'>mats.karlsson@farmbio.uu.se</a> [contributor]</li>
<li>John Johnson <a href='mailto:johndjohnson@gmail.com'>johndjohnson@gmail.com</a> [contributor]</li>
</ul>

pmxTools-package: pmxTools: Pharmacometric and Pharmacokinetic Toolkit

Description

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Author

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