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powerEQTL (version 0.3.1)

Power and Sample Size Calculation for Bulk Tissue and Single-Cell eQTL Analysis

Description

Power and sample size calculation for bulk tissue and single-cell eQTL analysis based on ANOVA, simple linear regression, or linear mixed effects model. It can also calculate power/sample size for testing the association of a SNP to a continuous type phenotype. Please see the reference: Dong X, Li X, Chang T-W, Scherzer CR, Weiss ST, Qiu W. (2021) .

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Version

Install

install.packages('powerEQTL')

Monthly Downloads

678

Version

0.3.1

License

GPL (>= 2)

Maintainer

Weiliang Qiu

Last Published

May 22nd, 2021

Functions in powerEQTL (0.3.1)

powerEQTL.ANOVA

Power Calculation for EQTL Analysis Based on Un-Balanced One-Way ANOVA
powerEQTL.scRNAseq

Power Calculation for Association Between Genotype and Gene Expression Based on Single Cell RNAseq Data
powerEQTL.SLR

Power Calculation for EQTL Analysis Based on Simple Linear Regression
simDat.eQTL.scRNAseq

Generate Gene Expression Levels Of One Gene And Genotypes Of One SNP For Subjects With Multiple Cells Based On ZINB Mixed Effects Regression Model
powerLME

Power Calculation for Simple Linear Mixed Effects Model
powerLMEnoCov

Power Calculation for Simple Linear Mixed Effects Model Without Covariate
powerEQTL.scRNAseq.sim

Power Calculation for Association Between Genotype and Gene Expression Based on Single Cell RNAseq Data via Simulation from ZINB Mixed Effects Regression Model