prLogistic (version 1.0)

Toenail: Toenail Data

Description

Data are from a multicenter study comparing two oral treatments for toe-nail infection, including information for 294 patients measured at 7 weeks, comprising a total of 1908 measurements. The outcome binary variable "onycholysis" indicates the degree of separation of the nail plate from the nail-bed (none or mild versus moderate or severe). Patients were evaluated at baseline (week 0) and at weeks 4, 8, 12, 24, 36, and 48 thereafter.

Usage

data(Toenail)

source

The data come from Data courtesy of Novoartis, Belgium (http://www.blackwellpublishing.com/rss/datasets/C4827r.txt)

References

De Backer, M., De Vroey, C., Lesaffre, E., Scheys, I., and De Keyser, P. (1998). Twelve weeks of continuous oral therapy for toenail onychomycosis caused by dermatophytes: A double-blind comparative trial of terbinafine 250 mg/day versus itraconazole 200 mg/day. Journal of the American Academy of Dermatology, 38, 57-63.

Lesaffre, E. and Spiessens, B. (2001). On the effect of the number of quadrature points in a logistic random-effects model: An example. Journal of the Royal Statistical Society, Series C, 50, 325-335.

Rabe-Hesketh S, Skrondal A (2008). Multilevel and Longitudinal Modeling Using Stata. Mahwah, NJ: Lawrence Erlbaum Associates. Second Edition.

Examples

data("Toenail", package = "prLogistic")
attach(Toenail)
summary(Toenail)