summary.exact

object

ordinalizer

<p>Additional parameters passed to the ordinalizer</p>

<p>Algorithmic (or 'rule-based') dose-escalation designs admit exact computation
of their outcomes. This method summarizes such an exact treatment in a manner
roughly parallel to that of <code>summary.precautionary</code>.</p>

Enhances various R packages that support the design and simulation
of phase 1 dose-escalation trials, adding diagnostics to examine
the safety characteristics of these designs in light of expected
inter-individual variation in pharmacokinetics and pharmacodynamics.
See Norris (2020b), "Retrospective analysis of a fatal dose-finding
trial" <arXiv:2004.12755> and (2020c) "What Were They Thinking?
Pharmacologic priors implicit in a choice of 3+3 dose-escalation design"
<arXiv:2012.05301>.

David C. Norris

summary.exact: Summarize an exact treatment of a dose-escalation design

Description

Usage

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