The coverage histogram is based on a single-cell whole-genome
sequencing data (scWGS) through MALBAK protocol. The accession number of the raw
data is SRR1301329. Only forward reads are used to generate the coverage
histogram.
Arguments
Details
A two-column matrix.
The first column is the frequency \(j = 1,2,\dots\); and the second column
is \(N_j\), the number of nucleotides in the genome covered exactly
\(j\) times.
References
Zong, C., Lu, S., Chapman, A. R., & Xie, X. S. (2012). Genome-wide detection
of single-nucleotide and copy-number variations of a single human cell.
Science, 338(6114), 1622-1626.