tree

<p>Example unrooted phylogenetic tree.</p>

datasets

Standardize the pre-processing of genomic variants before
performing a bacterial genome-wide association study (bGWAS). 'prewas'
creates a variant matrix (where each row is a variant, each column is a
sample, and the entries are presence - 1 - or absence - 0 - of the variant)
that can be used as input for bGWAS tools. When creating the binary variant
matrix, 'prewas' can perform 3 pre-processing steps including: dealing with
multiallelic SNPs, (optional) dealing with SNPs in overlapping genes, and
choosing a reference allele. 'prewas' can output matrices for use with both
SNP-based bGWAS and gene-based bGWAS. This method is described in Saund et
al. (2020) <doi:10.1099/mgen.0.000368>. 'prewas' can also provide
gene matrices for variants with specific annotations from the 'SnpEff'
software (Cingolani et al. 2012).

Katie Saund

prewas

Data Pre-Processing for Bacterial Genome-Wide Association
Studies

Zena Lapp

Stephanie Thiede

tree function

Format

Phylogenetic tree of example genomes — tree

Phylogenetic tree of example genomes

tree: Phylogenetic tree of example genomes

Description

Usage

Arguments

Format