pprimarycensored: Compute the primary event censored CDF for delays

Description

This function computes the primary event censored cumulative distribution function (CDF) for a given set of quantiles. It adjusts the CDF of the primary event distribution by accounting for the delay distribution and potential truncation at a maximum delay (D). The function allows for custom primary event distributions and delay distributions.

Usage

pprimarycensored(
  q,
  pdist,
  pwindow = 1,
  D = Inf,
  dprimary = stats::dunif,
  dprimary_args = list(),
  pdist_name = lifecycle::deprecated(),
  dprimary_name = lifecycle::deprecated(),
  ...
)
ppcens(
  q,
  pdist,
  pwindow = 1,
  D = Inf,
  dprimary = stats::dunif,
  dprimary_args = list(),
  pdist_name = lifecycle::deprecated(),
  dprimary_name = lifecycle::deprecated(),
  ...
)

Value

Vector of primary event censored CDFs, normalized by D if finite (truncation adjustment)

Arguments

q: Vector of quantiles
pdist: Distribution function (CDF). The package can identify base R distributions for potential analytical solutions. For non-base R functions, users can apply add_name_attribute() to yield properly tagged functions if they wish to leverage the analytical solutions.
pwindow: Primary event window
D: Maximum delay (truncation point). If finite, the distribution is truncated at D. If set to Inf, no truncation is applied. Defaults to Inf.
dprimary: Function to generate the probability density function (PDF) of primary event times. This function should take a value x and a pwindow parameter, and return a probability density. It should be normalized to integrate to 1 over [0, pwindow]. Defaults to a uniform distribution over [0, pwindow]. Users can provide custom functions or use helper functions like dexpgrowth for an exponential growth distribution. See pcd_primary_distributions() for examples. The package can identify base R distributions for potential analytical solutions. For non-base R functions, users can apply add_name_attribute() to yield properly tagged functions if they wish to leverage analytical solutions.
dprimary_args: List of additional arguments to be passed to dprimary. For example, when using dexpgrowth, you would pass list(min = 0, max = pwindow, r = 0.2) to set the minimum, maximum, and rate parameters
pdist_name: this argument will be ignored in future versions; use add_name_attribute() on pdist instead
dprimary_name: this argument will be ignored in future versions; use add_name_attribute() on dprimary instead
...: Additional arguments to be passed to pdist

Details

The primary event censored CDF is computed by integrating the product of the delay distribution function (CDF) and the primary event distribution function (PDF) over the primary event window. The integration is adjusted for truncation if a finite maximum delay (D) is specified.

The primary event censored CDF, $F_{\text{cens}}(q)$, is given by: $$ F_{\text{cens}}(q) = \int_{0}^{pwindow} F(q - p) \cdot f_{\text{primary}}(p) \, dp $$ where $F$ is the CDF of the delay distribution, $f_{\text{primary}}$ is the PDF of the primary event times, and $pwindow$ is the primary event window.

If the maximum delay $D$ is finite, the CDF is normalized by dividing by $F_{\text{cens}}(D)$: $$ F_{\text{cens,norm}}(q) = \frac{F_{\text{cens}}(q)}{F_{\text{cens}}(D)} $$ where $F_{\text{cens,norm}}(q)$ is the normalized CDF.

This function creates a primarycensored object using new_pcens() and then computes the primary event censored CDF using pcens_cdf(). This abstraction allows for automatic use of analytical solutions when available, while seamlessly falling back to numerical integration when necessary.

See methods(pcens_cdf) for which combinations have analytical solutions implemented.

Examples

Run this code

# Example: Lognormal distribution with uniform primary events
pprimarycensored(c(0.1, 0.5, 1), plnorm, meanlog = 0, sdlog = 1)

# Example: Lognormal distribution with exponential growth primary events
pprimarycensored(
  c(0.1, 0.5, 1), plnorm,
  dprimary = dexpgrowth,
  dprimary_args = list(r = 0.2), meanlog = 0, sdlog = 1
)