get_distance

Calculate difference measures using different metrics.

High-quality real-world data can be transformed into scientific
real-world evidence for regulatory and healthcare decision-making
using proven analytical methods and techniques. For example, propensity
score (PS) methodology can be applied to select a subset of real-world
data containing patients that are similar to those in the current clinical
study in terms of baseline covariates, and to stratify the selected
patients together with those in the current study into more homogeneous
strata. Then, statistical methods such as the power prior approach or
composite likelihood approach can be applied in each stratum to draw
inference for the parameters of interest. This package provides
functions that implement the PS-integrated real-world
evidence analysis methods such as
Wang et al. (2019) <doi:10.1080/10543406.2019.1657133>,
Wang et al. (2020) <doi:10.1080/10543406.2019.1684309>, and
Chen et al. (2020) <doi:10.1080/10543406.2020.1730877>.

Wei-Chen Chen

psrwe

PS-Integrated Methods for Incorporating Real-World Evidence in
Clinical Studies

Chenguang Wang

Trustees of Columbia University 

get_distance function

<dl><dt>cov0</dt>
<dd>Vector (or matrix for <code>metric = "mhb"</code>) of samples from the
first distribution.</dd>
<dt>cov1</dt>
<dd>Vector (or matrix for <code>metric = "mhb"</code>) of samples from the
second distribution.</dd>
<dt>metric</dt>
<dd>Metric to use for calculating the distance with options:<dl>
 <dt><code>ovl</code></dt>
<dd>Overlapping area</dd>
 (default)
 <dt><code>ksd</code></dt>
<dd>Kullback-Leibler distance</dd></dl></dd> <dt><code>astd</code></dt>
<dd>Standardized absolute mean difference</dd> <dt><code>std</code></dt>
<dd>Standardized mean difference</dd> <dt><code>abd</code></dt>
<dd>Absolute difference in means</dd> <dt><code>ley</code></dt>
<dd>Levy distance</dd> <dt><code>mhb</code></dt>
<dd>Mahalanobis distance</dd> <dt><code>omkss</code></dt>
<dd>One minus Kolmogorov-Smirnov statistic</dd>
</dl>

Arguments

Distance between two distributions — get_distance

<dl>

<dt>cov0</dt>
<dd>Vector (or matrix for <code>metric = "mhb"</code>) of samples from the
first distribution.</dd>


<dt>cov1</dt>
<dd>Vector (or matrix for <code>metric = "mhb"</code>) of samples from the
second distribution.</dd>


<dt>metric</dt>
<dd>Metric to use for calculating the distance with options:<dl>
 <dt><code>ovl</code></dt>
<dd>Overlapping area</dd>
 (default)
 <dt><code>ksd</code></dt>
<dd>Kullback-Leibler distance</dd>

 <dt><code>astd</code></dt>
<dd>Standardized absolute mean difference</dd>

 <dt><code>std</code></dt>
<dd>Standardized mean difference</dd>

 <dt><code>abd</code></dt>
<dd>Absolute difference in means</dd>

 <dt><code>ley</code></dt>
<dd>Levy distance</dd>

 <dt><code>mhb</code></dt>
<dd>Mahalanobis distance</dd>

 <dt><code>omkss</code></dt>
<dd>One minus Kolmogorov-Smirnov statistic</dd>


</dl></dd>

</dl>

get_distance: Distance between two distributions

Description

Usage

Value

Arguments

Examples