Learn R Programming

pvLRT (version 0.5.1)

Likelihood Ratio Test-Based Approaches to Pharmacovigilance

Description

A suite of likelihood ratio test based methods to use in pharmacovigilance. Contains various testing and post-processing functions.

Copy Link

Version

Install

install.packages('pvLRT')

Monthly Downloads

286

Version

0.5.1

License

GPL-3

Maintainer

Saptarshi Chakraborty

Last Published

March 6th, 2023

Functions in pvLRT (0.5.1)

rvold

FDA rotavirus vaccine dataset with 727 adverse events observed among "old" (non-infant; age >= 1 year) individuals
print.pvlrt

Print method for pvlrt objects
pvLRT-package

pvLRT: An R package implementing various Likelihood Ratio Test-based approaches to pharmacovigilance
lrt_poisson

Likelihood Ratio Test under the (vanilla, non-zero-inflated) Poisson model
lrt_zi_poisson

Pseudo Likelihood Ratio Test under the zero-inflated Poisson model with relative reporting rate parametrization
rv

FDA rotavirus vaccine dataset with 794 adverse events observed among combined old (age >= 1 year) and young (age < 1 year) individuals
rvyoung

FDA rotavirus vaccine dataset with 346 adverse events observed among young (infant -- 1 year) individuals
summary.pvlrt

Summary method for a pvlrt object
pvlrt

Pseudo Likelihood Ratio Test for determining significant AE-Drug pairs under Poisson and zero-inflated Poisson models for pharmacovigilance
r_contin_table_zip

Generate random contingency tables for adverse event (across rows) and drug (across columns) combinations given row and column marginal totals, embedded signals, and possibly with zero inflation
plot.pvlrt

Plotting method for a pvlrt object
%>%

Pipe operator
statin

FDA Statin dataset with 6039 adverse events
statin46

FDA Statin dataset with 46 adverse events
statin1491

FDA Statin dataset with 1491 adverse events
extract_lrstat_matrix

Extract various summary measures from a pvlrt object
convert_raw_to_contin_table

Convert raw AE-Drug incidence data into a contingency table
lovastatin

FDA lovastatin dataset
as.matrix.pvlrt

Casting a pvlrt object as a matrix of log LR statistics
all.equal.pvlrt

Test if two pvlrt objects are (Nearly) Equal
logLik.pvlrt

Overall Log-likelihood for a pvlrt object
gbca

FDA GBCA dataset with all observed 1707 adverse events
extract_AE_names

Extracting and setting AE and Drug names from a pvlrt object
faers22q3raw

FDA FAERS dataset for 2022 Q3
heatmap_pvlrt

Heatmap, barplot and bubbleplot displaying likelihood ratio test results in a pvlrt object