ci_for_prr

Mainly for use in <code>prr</code>. Produces (symmetric,
normality based) confidence bounds for the PRR, for a passed probability.
Called twice in <code>prr</code> to create confidence intervals.

Tools for performing disproportionality analysis using the information component, proportional reporting rate and the reporting odds ratio. The anticipated use is passing data to the da() function, which executes the disproportionality analysis. See Norén et al (2011) <doi:10.1177/0962280211403604> and Montastruc et al (2011) <doi:10.1111/j.1365-2125.2011.04037.x> for further details.

Michele Fusaroli

pvda

Disproportionality Functions for Pharmacovigilance

Oskar Gauffin

ci_for_prr function

<dl><dt>obs</dt>
<dd>Number of reports for the specific drug and event (i.e. the
observed count).</dd>
<dt>n_drug</dt>
<dd>Number of reports with the drug of interest.</dd>
<dt>n_event_prr</dt>
<dd>Number of reports with the event in the background.</dd>
<dt>n_tot_prr</dt>
<dd>Number of reports in the background.</dd>
<dt>conf_lvl_probs</dt>
<dd>The probabilities of the normal distribution, based on
a passed confidence level (<code>conf_lvl</code>) in <code>prr</code>. If
<code>sgn_lvl = .95</code> in <code>prr</code>, quantiles of the normal distribution will
be extracted at <code>sgn_lvl_probs</code> of 0.025 and 0.975.</dd></dl>

Arguments

Confidence intervals for Proportional Reporting Rate — ci_for_prr

<dl>

<dt>obs</dt>
<dd>Number of reports for the specific drug and event (i.e. the
observed count).</dd>


<dt>n_drug</dt>
<dd>Number of reports with the drug of interest.</dd>


<dt>n_event_prr</dt>
<dd>Number of reports with the event in the background.</dd>


<dt>n_tot_prr</dt>
<dd>Number of reports in the background.</dd>


<dt>conf_lvl_probs</dt>
<dd>The probabilities of the normal distribution, based on
a passed confidence level (<code>conf_lvl</code>) in <code>prr</code>. If
<code>sgn_lvl = .95</code> in <code>prr</code>, quantiles of the normal distribution will
be extracted at <code>sgn_lvl_probs</code> of 0.025 and 0.975.</dd>

</dl>

ci_for_prr: Confidence intervals for Proportional Reporting Rate

Description

Usage

Value

Arguments

See Also