pvrank (version 1.1)

Insuhyper: Role of insulin in endogenous hypertriglyceridemia

Description

Dietary carbohydrate accentuation of endogenous triglyceride production has been studied in 33 patients. No significant correlation existed between fasting plasma triglyceride concentration and either plasma glucose or free fatty acid concentrations after the high carbohydrate diet, nor was the degree of hypertriglyceridemia related to degree of obesity.

Usage

data(Insuhyper)

Format

In this dataset are described plasma glucose, insulin, FFA, and triglyceride responses to a high carbohydrate diet in 33 patients. The data frame includes 18 variables.

Age

years of age.

Sex

M=male, F=female

Height

cm

Weight

kg

PI

Ponderal Index, an estimate of obesity= Height(inches)/[weight(pounts)]^(1/3)

TG

Mean plasma triglyceride concentration during the last 2 wk of the high carbohydrate dietary period

PG8am

Plasma Glusose at 8 a.m. mg/100 ml

PG8am

Plasma Glusose at 9 a.m. mg/100 ml

PG8am

Plasma Glusose at 10 a.m.mg/100 ml

PG8am

Plasma Glusose average mg/100 ml

PI8am

Plasma Insulin at 8 a.m. $\mu$U/ml

PI8am

Plasma Insulin at 9 a.m. $\mu$U/ml

PI8am

Plasma Insulin at 10 a.m. $\mu$U/ml

PI8am

Plasma Insulin average $\mu$U/ml

PF8am

Plasma FFA at 8 a.m. $\mu$Eq/liter.

PF8am

Plasma FFA at 9 a.m. $\mu$Eq/liter

PF8am

Plasma FFA at 10 a.m. $\mu$Eq/liter

PF8am

Plasma FFA average $\mu$Eq/liter

Row names indicate name initials of the patients. The last four variables are omitted for 13 patients.

Source

Reaven, G. M. et al. (1967). "Role of insulin in endogenous hypertriglyceridemia". The Journal of Clinical Investigation, 46, 1756--1767.

Details

Authors have reported that the magnitude of plasma triglyceride response in man to diets either high or low in carbohydrate was highly correlated with both the plasma glucose and insulin responses elicited by that diet. The results confirm their previous finding of a high correlation between insulin and triglyceride responses. However, with inclusion of hyperglycemic patients there was no correlation found between plasma glucose response and the magnitude of the triglyceride elevation produced by the high carbohydrate diet. Finally, there was no correlation between hypertriglyceridemia and degree of obesity, or magnitude of the FFA response.

Examples

	data(Insuhyper)
	head(Insuhyper)