# read data
iron <- read_cross2(system.file("extdata", "iron.zip", package="qtl2"))
iron <- iron[,c("19","X")] # subset to chr 19 and X
# insert pseudomarkers into map
map <- insert_pseudomarkers(iron$gmap, step=1)
# calculate genotype probabilities
probs <- calc_genoprob(iron, map, error_prob=0.002)
# grab phenotypes and covariates; ensure that covariates have names attribute
pheno <- iron$pheno
covar <- match(iron$covar$sex, c("f", "m")) # make numeric
names(covar) <- rownames(iron$covar)
Xcovar <- get_x_covar(iron)
# permutations with genome scan (just 3 replicates, for illustration)
operm1 <- scan1perm(probs, pheno, addcovar=covar, Xcovar=Xcovar, n_perm=3)
operm2 <- scan1perm(probs, pheno, addcovar=covar, Xcovar=Xcovar, n_perm=3)
operm <- rbind(operm1, operm2)
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