sim1

design matrix (incorporating genotype probabilities from two loci), dn by df

a matrix of allele effects, f rows by d columns

a genetic covariance matrix, d by d

an error covariance matrix, d by d

a chromosome-specific kinship matrix, n by n

kinship

Simulate a single data set consisting of n subjects and 2 phenotypes for each

We implement an
adaptation of Jiang & Zeng's (1995) <https://www.genetics.org/content/140/3/1111> likelihood ratio test for testing
the null hypothesis of pleiotropy against the alternative hypothesis,
two separate quantitative trait loci. The test differs from that in Jiang & Zeng (1995) <https://www.genetics.org/content/140/3/1111>
and that in Tian et al. (2016) <doi:10.1534/genetics.115.183624> in
that our test accommodates multiparental populations.

sim1: Simulate a single data set consisting of n subjects and 2 phenotypes for each

Description

Usage

Arguments