ppc.fitPBK

Plots posterior predictive check for <code>fitPBK</code>

Fit and simulate any kind of
physiologically-based kinetic ('PBK') models whatever the number of compartments.
Moreover, it allows to account for any link between pairs of compartments, as
well as any link of each of the compartments with the external medium. Such
generic PBK models have today applications in pharmacology (PBPK models) to
describe drug effects, in toxicology and ecotoxicology (PBTK models) to describe
chemical substance effects. In case of exposure to a parent compound (drug or
chemical) the 'rPBK' package allows to consider metabolites, whatever their number
and their phase (I, II, ...). Last but not least, package 'rPBK' can also be used for
dynamic flux balance analysis (dFBA) to deal with metabolic networks. See also
Charles et al. (2022) <doi:10.1101/2022.04.29.490045>.

Virgile Baudrot

rPBK

Inference and Prediction of Generic Physiologically-Based
Kinetic Models

Sandrine Charles

Christelle Lopes

Ophélia Gestin

Dominique Lamonica

Aurélie Siberchicot

ppc function

<dl><dt>x</dt>
<dd>an object used to select a method <code>ppc</code></dd>
<dt>...</dt>
<dd>Further arguments to be passed to generic methods</dd></dl>

Arguments

Posterior predictive check plot — ppc

<dl>

<dt>x</dt>
<dd>an object used to select a method <code>ppc</code></dd>


<dt>...</dt>
<dd>Further arguments to be passed to generic methods</dd>

</dl>

ppc: Posterior predictive check plot

Description

Usage

Value

Arguments

Examples