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randomizeBE (version 0.3-6)

Create a Random List for Crossover Studies

Description

Contains a function to randomize subjects, patients in groups of sequences (treatment sequences). If a blocksize is given, the randomization will be done within blocks. The randomization may be controlled by a Wald-Wolfowitz runs test. Functions to obtain the p-value of that test are included. The package is mainly intended for randomization of bioequivalence studies but may be used also for other clinical crossover studies. Contains two helper functions sequences() and williams() to get the sequences of commonly used designs in BE studies.

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Install

install.packages('randomizeBE')

Monthly Downloads

230

Version

0.3-6

License

GPL (>= 2.0)

Maintainer

D. Labes

Last Published

August 19th, 2023

Functions in randomizeBE (0.3-6)

RL4

(Block) randomization of subjects, patients into sequence groups
print.rl4

S3 method print for class "rl4"
williams

Construct sequences of a Williams design
runs.pvalue

2-sided p-value of the runs test
sequences

Obtain sequences for BE study designs
pruns.exact

Exact cumulative distribution function of runs test