Sampling algorithm for gbcd
gbcdRand(N, rho, K = 2)
integer for the total sample size of the trial.
nonnegative parameter which my be adjusted according to how strongly it is
desired to balance the experiment. If rho = 1
, we have Wei's urn design with
alpha = 0
. If rho = 0
, we have complete randomization.
number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment).
A vector with the allocation sequence for a clinical trial.
It will contain a zero (resp. 1) at position i
, when patient i
is allocated to treatment A (resp. B).
R. L. Smith (1984) Sequential treatment allocation using biased coin designs. Journal of the Royal Statistical Society B, 46, 519-543. W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley, 64-65