Represents the Maximal Procedure.
mpPar(N, mti, ratio = c(1, 1), groups = LETTERS[1:2])
integer for the total sample size of the trial.
maximum tolerated imbalance in patient numbers during the trial.
vector of length K
. The total sample number N
and
all used block lengths (bc
) have to be divisible by sum(ratio)
.
character vector of labels for the different treatments.
S4
object of the class mpPar
.
Fix the total sample size N
and the mti
. Afterwards, the patients
are assigend to each treatment arm according to the ratio
.
All randomization sequences are equiprobable.
V.W. Berger, A. Ivanova and M.D. Knoll (2003) Minimizing predictability while retaining balance through the use of less restrective randomization procedures. Statistics in Medicine, 19, 3017-28.
Other randomization procedures: abcdPar
,
bbcdPar
, bsdPar
,
chenPar
, crPar
,
createParam
, ebcPar
,
gbcdPar
, hadaPar
,
pbrPar
, rarPar
,
rpbrPar
, rtbdPar
,
tbdPar
, udPar