Represents the randomization procedure Randomized Permuted Block Randomization.
rpbrPar(N, rb, K = 2, ratio = rep(1, K), groups = LETTERS[1:K],
filledBlock = FALSE)
integer for the total sample size of the trial.
block lengths of the blocks that can be selected equiprobable at random.
number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment).
vector of length K
. The total sample number N
and
all used block lengths (bc
) have to be divisible by sum(ratio)
.
character vector of labels for the different treatments.
logical
whether the last block should be filled or not.
S4
object of the class rpbrPar
.
Fix the possible random block lengths rb
, the number of treatment groups K
,
the sample size N
and the vector of the ratio
. Afterwards, one block length is
randomly selected of the random block lengths. The patients are assigned
according to the ratio to the corresponding treatment groups. This procedure is repeated
until N
patients are assigned. Within each block all possbible
randomization sequences are equiprobable.
W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley.
Other randomization procedures: abcdPar
,
bbcdPar
, bsdPar
,
chenPar
, crPar
,
createParam
, ebcPar
,
gbcdPar
, hadaPar
,
mpPar
, pbrPar
,
rarPar
, rtbdPar
,
tbdPar
, udPar