Represents the expected power of the individual randomization sequences.
setPower(d, method, alpha = 0.05)
S4
object of class power
, a formal representation of the
issue of power in a clinical trial.
effect size.
character string, should be one of "sim"
or "exact"
, see Description.
significance level.
The attained power of an individual randomization sequence can be an issue
in the design of a clinical trial. The power of a randomization sequence is
computed depending on the effect size d
and the difference in
group sizes.
If method="sim"
, the object represents the simulated power of an
individual randomization sequence. When calling assess
for a
power
object with method="sim"
, one test decision is computed
for each randomization sequence of randSeq
. The power is the
proportion of falsely (correctly) rejected null hypotheses.
If method="exact"
, the object represents the exact power of an
individual randomization sequence. When calling assess
for a
power
object with method="exact"
, the exact p-value
of each randomization sequence is computed. So far, this is only supported
for normal endpoints. Then the power is the sum of the corresponding
quantiles of the noncentral t-distribution.
Other issues:
chronBias
,
combineBias()
,
corGuess
,
imbal
,
issue
,
selBias