Reactome incorporate manually curated human reactions and PANTHER's protein homology data to Computationally infer events in other eukaryotic species.
rba_reactome_orthology(event_ids, species_dbid, ...)List containing found Orthologous event(s) in your supplied species and their pertinent information.
Human Reactome event ID(s) to retrieve their orthologous events.
Reactome database ID (DbId) of the target species. (e.g
Mus musculus is 48892). See
rba_reactome_species or
Reactome
Data Schema: Entries: Species.
rbioapi option(s). See rba_options's
arguments manual for more information on available options.
"POST https://reactome.org/ContentService/data/orthologies/ids/ species/{speciesId}"
In version 73 (11 June 2020), using an orthology-based approach,
Homo sapiens events was projected to 18,654 orthologous pathways (with
81,835 orthologous proteins) in 15 non-human species.
See
Reactome Computationally Inferred Events for more information.
Marc Gillespie, Bijay Jassal, Ralf Stephan, Marija Milacic, Karen Rothfels, Andrea Senff-Ribeiro, Johannes Griss, Cristoffer Sevilla, Lisa Matthews, Chuqiao Gong, Chuan Deng, Thawfeek Varusai, Eliot Ragueneau, Yusra Haider, Bruce May, Veronica Shamovsky, Joel Weiser, Timothy Brunson, Nasim Sanati, Liam Beckman, Xiang Shao, Antonio Fabregat, Konstantinos Sidiropoulos, Julieth Murillo, Guilherme Viteri, Justin Cook, Solomon Shorser, Gary Bader, Emek Demir, Chris Sander, Robin Haw, Guanming Wu, Lincoln Stein, Henning Hermjakob, Peter D’Eustachio, The reactome pathway knowledgebase 2022, Nucleic Acids Research, 2021;, kab1028, https://doi.org/10.1093/nar/gkab1028
Griss J, Viteri G, Sidiropoulos K, Nguyen V, Fabregat A, Hermjakob H. ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. Mol Cell Proteomics. 2020 Sep 9. doi: 10.1074/mcp. PubMed PMID: 32907876.
rba_reactome_analysis_species
# \donttest{
rba_reactome_orthology(event_ids = c("R-HSA-6799198", " R-HSA-72764"),
species_dbid = 49633)
# }
Run the code above in your browser using DataLab