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rcellminer (version 1.4.2)

drugDB: CellMiner Drug Response Values

Description

CellMiner Drug Response Values

Arguments

concept

rcellminer

Details

A list containing response values and annotations:
  • act
{Z-scores of the averaged negative log GI (growth inhibition) 50 values across repeats for the NCI-60; assay described here: http://dtp.nci.nih.gov/branches/btb/ivclsp.html} annot {
  • id
{Dataset identifier; NOTE: DO NOT use this column; the NSC is the primary drug identifier} nsc {National Service Center identifier; the primary drug identifier} name {Compound name} brand_name {Brand name for the compound, if sold commericially} formula {Compound chemical formula} testing_status {Information on whether it is known if the compound is FDA approved or undergoing testing in clinical trials} source {TODO} smiles {Compound chemical structure as a SMILES string} weight {Compound chemical weight in g/mol} mechanism {Pharmacological mechanism of action} confidential_flag {A flag to indicate if compound information is public} total_probes {TODO} total_good_probes {TODO} low_correlations {TODO} failure_reason {TODO} cas {CAS Registry Number; NOTE: Due to data restrictions PubChem IDs are the preferred mapping ID to other datasets} pubchem_id {PubChem ID} }

References

http://discover.nci.nih.gov/cellminer/loadDownload.do