Learn R Programming

refineR (version 2.0.0)

getRI: Method to calculate reference intervals (percentiles) for objects of class 'RWDRI'

Description

Method to calculate reference intervals (percentiles) for objects of class 'RWDRI'

Usage

getRI(
  x,
  RIperc = c(0.025, 0.975),
  CIprop = 0.95,
  pointEst = c("fullDataEst", "medianBS"),
  Scale = c("original", "transformed", "zScore"),
  UMprop = 0.9,
  ...
)

Value

		(data.frame) with columns for percentile, point estimate, bootstrap-based confidence intervals and uncertainty margins.

Arguments

x

(object) of class 'RWDRI'

RIperc

(numeric) value specifying the percentiles, which define the reference interval

CIprop

(numeric) value specifying the central region for estimation of confidence intervals

pointEst

(character) specifying the point estimate determination: (1) using the full dataset ("fullDataEst"), (2) calculating the median model from all bootstrap samples ("medianBS"), (2) works only if NBootstrap > 0

Scale

(character) specifying if percentiles are calculated on the original scale ("or") or the transformed scale ("tr") or the z-Score scale ("z")

UMprop

(numeric) value specifying the central region for estimation of uncertainty margins

...

calcUCMargins argument (logical) disabling the calculation of uncertainty margins when set to FALSE, n argument (integer) specifying the theoretical sample size used for uncertainty margin calculation default (n = 120), asymmetryCorr argument (logical) disabling the asymmetry correction when set to FALSE

Author

Christopher Rank christopher.rank@roche.com, Tatjana Ammer tatjana.ammer@roche.com, Matthias Beck matthias.beck.mb1@roche.com