# hazard.ratio.plot

##### Hazard Ratio Plot

The `hazard.ratio.plot`

function repeatedly estimates Cox
regression coefficients and confidence limits within time intervals.
The log hazard ratios are plotted against the mean failure/censoring
time within the interval. Unless `times`

is specified, the number of
time intervals will be \(\max(round(d/e),2)\), where \(d\) is the
total number
of events in the sample. Efron's likelihood is used for estimating
Cox regression coefficients (using `coxph.fit`

). In the case of
tied failure times, some intervals may have a point in common.

- Keywords
- survival

##### Usage

```
hazard.ratio.plot(x, Srv, which, times=, e=30, subset,
conf.int=.95, legendloc=NULL, smooth=TRUE, pr=FALSE, pl=TRUE,
add=FALSE, ylim, cex=.5, xlab="t", ylab, antilog=FALSE, …)
```

##### Arguments

- x
a vector or matrix of predictors

- Srv
a

`Surv`

object- which
a vector of column numbers of

`x`

for which to estimate hazard ratios across time and make plots. The default is to do so for all predictors. Whenever one predictor is displayed, all other predictors in the`x`

matrix are adjusted for (with a separate adjustment form for each time interval).- times
optional vector of time interval endpoints. Example:

`times=c(1,2,3)`

uses intervals`[0,1), [1,2), [2,3), [3+)`

. If times is omitted, uses intervals containing`e`

events- e
number of events per time interval if times not given

- subset
vector used for subsetting the entire analysis, e.g.

`subset=sex=="female"`

- conf.int
confidence interval coverage

- legendloc
location for legend. Omit to use mouse,

`"none"`

for none,`"ll"`

for lower left of graph, or actual x and y coordinates (e.g.`c(2,3)`

)- smooth
also plot the super--smoothed version of the log hazard ratios

- pr
defaults to

`FALSE`

to suppress printing of individual Cox fits- pl
defaults to

`TRUE`

to plot results- add
add this plot to an already existing plot

- ylim
vector of

`y`

-axis limits. Default is computed to include confidence bands.- cex
character size for legend information, default is 0.5

- xlab
label for

`x`

-axis, default is`"t"`

- ylab
label for

`y`

-axis, default is`"Log Hazard Ratio"`

or`"Hazard Ratio"`

, depending on`antilog`

.- antilog
default is

`FALSE`

. Set to`TRUE`

to plot anti-log, i.e., hazard ratio.- ...
optional graphical parameters

##### See Also

##### Examples

```
# NOT RUN {
n <- 500
set.seed(1)
age <- 50 + 12*rnorm(n)
cens <- 15*runif(n)
h <- .02*exp(.04*(age-50))
d.time <- -log(runif(n))/h
label(d.time) <- 'Follow-up Time'
e <- ifelse(d.time <= cens,1,0)
d.time <- pmin(d.time, cens)
units(d.time) <- "Year"
hazard.ratio.plot(age, Surv(d.time,e), e=20, legendloc='ll')
# }
```

*Documentation reproduced from package rms, version 5.1-4, License: GPL (>= 2)*