roar-package:
Identify differential APA usage from RNA-seq alignments
Description
Identify preferential usage of APA sites,
comparing two biological conditions, starting from known alternative sites and
alignments obtained from standard RNA-seq experiments.
Details
|
Package: |
| roar |
|
Type: |
| Package |
|
Version: |
| 0.1.1 |
|
Date: |
| 2013-05-04 |
|
License: |
| GPL-3 |
The codeRoarDataset class exposes methods to perform the whole analysis, in order to
identify genes with preferential expression of long/short isoforms in a condition with respect to
another one. The needed input data are alignments deriving from RNA-seq experiments of the
two conditions and a set of coordinates of APA sites for genes with an alternative APA site
proximal to the one used ``normally''.