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robustMVMR (version 0.3.1)

IL1_LUSC: IL-1 and squamous cell lung cancer

Description

Data from two genome-wide association studies for protenomics and the internal lung cancer consortium study. The outcome is the squamous cell lung cancer, and the exposures are interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist.

Usage

data(IL1_LUSC)

Arguments

Format

An matrix contains the genetic associations of the exposures and the outcome.

References

  • 1. Sun et al. (2018) Genomic atlas of the human plasma proteome. Nature, 558(7708):73-79

  • 2. Ahola-Olli et al. (2017) Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Am J Hum Genet,100(1):40-50.

  • 3. Wang et al. (2014) Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet, 46(7):736-41.