param_effectMeasure

<p>Criterion for treatment arm selection, either based on test statistic 
(<code>"testStatistic"</code>) or effect difference (<code>"effectDifference"</code>), 
default is <code>"effectDifference"</code>.</p>

effectMeasure

<p>Parameter Description: Effect Measure</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_effectMeasure: Parameter Description: Effect Measure

Description

Arguments