param_pi1_rates

<p>A numeric value or vector that represents the assumed probability in 
the active treatment group if two treatment groups 
are considered, or the alternative probability for a one treatment group design, 
default is <code>seq(0.2, 0.5, 0.1)</code> (power calculations and simulations) or 
<code>seq(0.4, 0.6, 0.1)</code> (sample size calculations).</p>

<p>Parameter Description: Pi (1) for Rates</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_pi1_rates: Parameter Description: Pi (1) for Rates

Description

Arguments