param_effectMatrix

<p>Matrix of effect sizes with <code>activeArms</code> columns and number of rows 
reflecting the different situations to consider.</p>

effectMatrix

<p>Parameter Description: Effect Matrix</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_effectMatrix: Parameter Description: Effect Matrix

Description

Arguments