param_userAlphaSpending

<p>The user defined alpha spending. 
Numeric vector of length <code>kMax</code> containing the cumulative 
alpha-spending (Type I error rate) up to each interim stage: <code>0 &lt;= alpha_1 &lt;= ... &lt;= alpha_K &lt;= alpha</code>.</p>

userAlphaSpending

<p>Parameter Description: User Alpha Spending</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_userAlphaSpending: Parameter Description: User Alpha Spending

Description

Arguments