param_informationRates

<p>The information rates (that must be fixed prior to the trial), 
default is <code>(1:kMax) / kMax</code>.</p>

informationRates

<p>Parameter Description: Information Rates</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_informationRates: Parameter Description: Information Rates

Description

Arguments