param_thetaH1

<p>If specified, the value of the alternative under which 
the conditional power or sample size recalculation calculation is performed.</p>

thetaH1

<p>Parameter Description: Effect Under Alternative</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_thetaH1: Parameter Description: Effect Under Alternative

Description

Arguments