param_typeOfComputation

<p>Three options are available: <code>"Schoenfeld"</code>, <code>"Freedman"</code>, <code>"HsiehFreedman"</code>, 
the default is <code>"Schoenfeld"</code>. For details, see Hsieh (Statistics in Medicine, 1992). 
For non-inferiority testing (i.e., <code>thetaH0 != 1</code>), only Schoenfeld's formula can be used.</p>

typeOfComputation

<p>Parameter Description: Type Of Computation</p>

internal

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Friedrich Pahlke

param_typeOfComputation: Parameter Description: Type Of Computation

Description

Arguments